Metabolitos aislados de raputia heptaphylla y esenbeckia alata (rutaceae) y síntesis de precursores de análogos de alcaloides quinolínicos

Coy Barrera, Carlos A.; Cuca Suárez, Luis E.

dc.creator	Coy Barrera, Carlos A.
dc.creator	Cuca Suárez, Luis E.
dc.date	2015-09-02
dc.date.accessioned	2022-03-24T17:51:56Z
dc.date.available	2022-03-24T17:51:56Z
dc.identifier	https://journal.poligran.edu.co/index.php/elementos/article/view/617
dc.identifier	10.15765/e.v5i5.617
dc.identifier.uri	http://hdl.handle.net/10823/6261
dc.description	Abstract. Previous studies on the Esenbeckia alata and Raputia heptaphylla,both species belonging to the Rutaceae family, have shownimportant results with respect to their chemistry. These species havesecondary metabolites (coumarins and alkaloids mainly), which act aschemotaxonomic markers. This paper presents, for the first time, the phytochemicalwork and isolated metabolites in these species: four coumarins:bergapten, xanthyletin, xanthotoxin, 3-isoprenyl-4-methoxy-coumarin;four alkaloids: skinmianine, kokusaginine, dictamnine, and 1-methyl-2-methoxy-4-quinolone; two lignans: sesamin and mesodihydroguaiareticacid; two sterols: -sitosterol, stigmasterol; and a pentacyclic triterpene:lupeol that have been isolated from leaves of E. alata. Five alkaloids7-methoxy-2,2-dimethyl-2,6-dihidro-piran[3,2,c] quinolin-5-one, flindersiamine,skinmianine, kokusaginine and dictamnine that have been isolatedfrom leaves of R. heptaphylla. Moreover, it presents a new method byobtaining quinolone alkaloid analogue precursors trough the condensationsof Mannich adduct vinylogous and aldehydes followed by radicalcyclization to obtain products with high regio- and stereoselectivity.	es-ES
dc.format	application/pdf
dc.language	spa
dc.publisher	Politécnico Grancolombiano	es-ES
dc.relation	https://journal.poligran.edu.co/index.php/elementos/article/view/617/639
dc.rights	Derechos de autor 2015 ELEMENTOS	es-ES
dc.source	ELEMENTOS; Vol. 5 No. 5 (2015): Elementos	en-US
dc.source	Elementos; Vol. 5 Núm. 5 (2015): Elementos	es-ES
dc.source	2248-5252
dc.source	2027-923X
dc.source	10.15765/e.v5i5
dc.subject	Raputia	es-ES
dc.subject	Rutaceae	es-ES
dc.subject	Esenbeckia	es-ES
dc.subject	quinolinic alkaloids	es-ES
dc.title	Metabolitos aislados de raputia heptaphylla y esenbeckia alata (rutaceae) y síntesis de precursores de análogos de alcaloides quinolínicos	es-ES
dc.type	info:eu-repo/semantics/article
dc.type	info:eu-repo/semantics/publishedVersion
dc.type	Artículo revisado por pares	es-ES

Ficheros en el ítem

Ficheros	Tamaño	Formato	Ver
No hay ficheros asociados a este ítem.

Este ítem aparece en la(s) siguiente(s) colección(ones)

Elementos [66]
Revista semestral de divulgación académica en ingeniería

Mostrar el registro sencillo del ítem